What is the effect on solubilization and absorption in the stomach with obesity?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Prepare for the MTM Pediatric Obesity Test with our comprehensive study aids. Use flashcards and multiple choice questions, each with detailed explanations and hints. Ensure you're ready for the exam!

Multiple Choice

What is the effect on solubilization and absorption in the stomach with obesity?

Explanation:
In obesity, changes in the stomach’s environment and movement affect how drugs dissolve and are absorbed there. The stomach may have altered pH and slower or differently patterned motility and mixing, which reduces the dissolution of drugs that rely on the acidic, well-mixed gastric environment. This leads to less solubilization in the stomach and, as a result, less drug absorption occurring there. Although much of oral absorption happens later in the small intestine, the stomach’s reduced ability to solubilize and begin absorbing certain compounds in obesity makes both solubilization and absorption decrease.

In obesity, changes in the stomach’s environment and movement affect how drugs dissolve and are absorbed there. The stomach may have altered pH and slower or differently patterned motility and mixing, which reduces the dissolution of drugs that rely on the acidic, well-mixed gastric environment. This leads to less solubilization in the stomach and, as a result, less drug absorption occurring there. Although much of oral absorption happens later in the small intestine, the stomach’s reduced ability to solubilize and begin absorbing certain compounds in obesity makes both solubilization and absorption decrease.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy