Among common anti-obesity medications, which is NOT approved for weight management due to limited efficacy?

• A. Orlistat
• B. Lisdexamfetamine
• C. Phentermine
• D. Liraglutide

Answer: (B)

Weight-management medications are judged by how much weight they help patients lose and whether they have approved uses for obesity in the target age group. Among common options, the ones with regulatory approval for obesity management show meaningful weight loss and have established safety data in the appropriate populations. Lisdexamfetamine is not approved for treating obesity because the weight loss benefits are limited and there are safety and misuse concerns with stimulant medications. In contrast, other listed meds have approvals and evidence supporting their use for weight management in the right contexts. Therefore, lisdexamfetamine is the one not approved for weight management due to limited efficacy.